Quick Overview for SHP1 Protein (ABIN666674)
Target
See all SHP1 (PTPN6) ProteinsProtein Type
Origin
Source
Application
Purity
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Characteristics
- SHP-1, Human, Recombinant, E.coli
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Protein-tyrosine Phosphatase 1C (PTPN6) (AA 1-595) protein (His tag)
custom-made PTPN6 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Protein-tyrosine Phosphatase 1C (PTPN6) (AA 1-595) protein (His tag)custom-made PTPN6 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Protein-tyrosine Phosphatase 1C (PTPN6) (AA 5-163) protein (His-IF2DI Tag)PTPN6 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Protein-tyrosine Phosphatase 1C (PTPN6) (AA 1-597) protein (GST tag)PTPN6 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA, PAA
Protein-tyrosine Phosphatase 1C (PTPN6) (AA 207-597) (Active) protein (GST tag,His tag)PTPN6 Origin: Mouse Host: Baculovirus infected Insect Cells Recombinant > 85 % as determined by SDS-PAGE Active
Protein-tyrosine Phosphatase 1C (PTPN6) (Active) proteinPTPN6 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % pure SDS Active
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/ml (determined by Bradford assay)
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Buffer
- Liquid. 25 mM Tris-HCl, pH7.5, 2 mM beta-mercaptoethanol, 1 mM EDTA. 1mMDTT, 20%Glycerol
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Storage
- 4 °C
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- SHP1 (PTPN6) (Protein-tyrosine Phosphatase 1C (PTPN6))
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Alternative Name
- SHP-1
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Background
- The protein coding region of the catalytic domain of SHP-1 (amino acids 243-541) was cloned into an E. coli expression vector. The catalytic domain of SHP-1 was overexpressed as insoluble protein aggregates (inclusion bodies). The recombinant SHP-1 protein was purified by FPLC gel-filtration chromatography, after refolding of the isolated inclusion bodies in a redox buffer. Additional amino acid(Met) is attached at N-terminus. Synonyms: PTPN6, HCP, PTP1C, Tyrosine-protein phosphatase non-receptor type 6, EC 3.1.3.48, Protein-tyrosine phosphatase 1C, PTP-1C, Hematopoietic cell protein-tyrosine phosphatase, SH-PTP1, Protein-tyrosine phosphatase SHP-1, PTPN6, HCP, HCPH, SHP1, HPTP1C, SHP-1L EC 3.1.3.48, Protein tyrosine phosphatase non-receptor type 6 isoform 1, 70 kda SHP1L protein, Hematopoietic cell phosphatase, Hematopoietic cell protein tyrosine phosphatase, HPTP 1C, Protein tyrosine phosphatase 1C, Protein tyrosine phosphatase SHP 1, Protein tyrosine phosphatase SHP1, PTP 1C, PTPN 6, SH PTP 1, SH PTP1, SHP 1, SHP 1L, SHP1L, SHPTP 1, SHPTP1, Tyrosine protein phosphatase non receptor type 6. NCBI no.: NP_002822
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Molecular Weight
- 34.3 kDa (300 aa), confirmed by MALDI-TOF.
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Pathways
- JAK-STAT Signaling, TCR Signaling, TLR Signaling, Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Response to Growth Hormone Stimulus, Regulation of Leukocyte Mediated Immunity, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, BCR Signaling
Target
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